Pulmonary Embolism
Pulmonary Embolism
What is Pulmonary Embolism?
Pulmonary embolism (PE) is a blockage of the pulmonary arteries in the lungs. It is most commonly caused by blood clots that travel to the lungs from the venous (vein) system. Most often, the clots form in the leg veins or pelvic veins (a condition known as deep vein thrombosis or DVT). Because pulmonary emboli can lead to acute and significant strain on the heart, this condition can be potentially life threatening.
Pulmonary emboli can present as acute PE or chronic PE:
Acute PE is a new obstruction causing acute onset heart strain. Acute PE often needs immediate treatment with clot busters and blood thinning medications. Acute PE is the third most common cause of death from cardiovascular disease after heart attack and stroke.
Chronic PE is a more insidious presentation that includes heart failure with gradual progressive symptoms. Chronic PE occurs when the leftover clot turns into scar tissue inside the pulmonary arteries. In a small percentage of patients, chronic PE can lead to elevated blood pressure in the pulmonary arteries over time, developing into chronic thromboembolic pulmonary hypertension, or CTEPH, a rare type of pulmonary hypertension.
What are the risk factors for pulmonary embolism?
Any blood clot increases the risk of a pulmonary embolism. Risk factors for blood clot formation include:
Genetic blood clotting disorders
Inactivity for long periods of time; for example, during lengthy automobile or airplane travel or long bed rest
Cancer
Pregnancy and childbirth
Taking birth control pills
Chronic medical illness
Our Approach
At University of Michigan Health, patients with a pulmonary embolism are treated with a specialized multidisciplinary team-based approach. Our team includes specialists from cardiology, vascular medicine, hospital medicine, hematology, pulmonary hypertension, interventional cardiology, interventional radiology and cardiothoracic surgery.
The U-M Health Frankel Cardiovascular Center has dedicated specialized pulmonary embolism and pulmonary hypertension clinics where specialists from various disciplines work in sync to deliver high-quality, personalized advanced care to these patients.
We have a dedicated 24-hour on-call pulmonary embolism response team (PERT). A PERT consultation with the patient follows an extensive evaluation and discussion among various subspecialists, including medical management and interventional therapies.
Patients have access to all available and upcoming novel investigations for the entire spectrum of pulmonary embolic disease, including acute PE, chronic PE and CTEPH. Our ability to work in a multidisciplinary fashion differentiates our program and allows patients access to various specialists and therapies.
The U-M Health Frankel Cardiovascular Center has the most advanced surgical and interventional programs in the region for the treatment of acute and chronic PE and CTEPH.
Appointment Information
To make an appointment to discuss treatment for pulmonary embolism, call the University of Michigan Health Frankel Cardiovascular Call Center at 888-287-1082.
What are the symptoms of pulmonary embolism?
The clinical presentation of acute pulmonary embolism is:
Shortness of breath
Chest pain
Rapid or irregular heartbeat
Fainting episodes
Lightheadedness
How is Pulmonary Embolism diagnosed?
A pulmonary embolism can be diagnosed in several ways, including:
Computed tomography (CT): Scan of the chest (the most common method of diagnosing a PE and DVT)
Chest X-ray: Provides a picture of the lungs and chest and helps rule out other possible conditions
Electrocardiogram (ECG): Helps differentiate a PE from a heart attack
Ventilation perfusion scan: A quick, non-invasive screening tool to look for CTEPH
Echocardiogram: Helps identify any heart dysfunction
How is Pulmonary Embolism treated?
Medical management: Patients with a pulmonary embolism can be treated with blood thinners, also known as anticoagulants. These medications can be given intravenously, by injection under the skin, or by mouth. Blood thinners prevent a new clot from forming so that our body can begin the process of breaking down an existing clot.
Advanced, non-surgical therapies:
Catheter-directed thrombolysis, a minimally invasive treatment to dissolve blood clots and improve blood flow to prevent damage to tissues and organs. During this procedure, which is performed in a catheterization laboratory, a clot-dissolving medication called thrombolytic is delivered in the pulmonary blood clot through a thin plastic tube, or catheter, placed in the pulmonary arteries typically from the groin, neck or behind the knee vein. The catheter is guided using X-ray imaging.
Catheter-based thrombus removal, also known as a mechanical thrombectomy, involves a thin tube or catheter to remove large blood clots from an artery. Michigan Medicine offers all the current approved non-surgical catheter-based technologies as well as numerous investigational studies.
Inferior vena cava filter, a procedure that involves a vein filter implanted via a thin wire into the vena cava, the main vein leading from the legs to the right side of the heart. The vein filter prevents clots from traveling to the heart or lungs. These devices prevent future clot migration from legs to lungs and are placed temporarily if a patient’s bleeding risk with conventional blood thinners is very high.
Patient Resources
Locations
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Cardiology Clinic | Frankel Cardiovascular Center 1425 E Ann St
Floor 3 Reception C
Ann Arbor, MI 48109-5856Get Directions -
Vascular & Interventional Radiology Clinic | Cardiovascular Center 1425 E Ann St
Floor 3 Reception B
Ann Arbor, MI 48109-5856Get Directions -
Venous Management Clinic | Frankel Cardiovascular Center 1425 E Ann St
Floor 3 Reception B
Ann Arbor, MI 48109-5856Get Directions
Doctors
Kareem M Ballut, MD
Clinical Assistant Professor
Cardiovascular Disease, Critical Care Medicine, Advanced Heart Failure & Transplant Cardiology, Internal Medicine
Geoffrey Douglas Barnes, MD, MSc
Associate Professor
Cardiovascular Disease, Internal Medicine
James Barklow Froehlich, MD
Clinical Professor
Cardiovascular Disease, Internal Medicine
Paul James Grant, MD
Clinical Professor
Internal Medicine, Hospitalist
Minhajuddin Syad Khaja, MD
Clinical Professor
Vascular & Interventional Radiology, Diagnostic Radiology, Interventional Radiology & Diagnostic Radiology
Providers
Christine Elizabeth Edwards, NP, DNP
Advanced Practice Nurse
Nurse Practitioner
Clare Helen Harris, NP
Advanced Practice Nurse
Nurse Practitioner, Nurse Practitioner - Primary Care, Nurse Practitioner - Adult Health
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