Peptic Ulcer Disease

Condition Basics

What are peptic ulcers, and what causes them?

Peptic ulcers in the stomach and duodenum.

Peptic ulcers are sores in the inner lining of the stomach or upper small intestine. They form when the digestive juices produced by the stomach erode or eat away the lining of the digestive tract. Peptic ulcers may form in the lining of the stomach (gastric ulcers) or just below the stomach, at the start of the small intestine (duodenal ulcers).

The most common causes of peptic ulcers are infection with Helicobacter pylori (H. pylori) bacteria and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs include aspirin, ibuprofen (Advil or Motrin), and naproxen (Aleve).

What are the symptoms?

Symptoms of a peptic ulcer can include a burning, aching, or gnawing pain between the belly button and the breastbone, and belly pain that is temporarily relieved by taking an antacid. Symptoms can also include back pain, loss of appetite, bloating, nausea, and vomiting. Some people have no symptoms.

How are they diagnosed?

Your doctor will ask about your symptoms and do a physical exam. Your doctor may do some simple tests (using your blood, breath, or stool) to look for signs of H. pylori infection. You may have an endoscopy to check the inside of your esophagus, stomach, and small intestine.

How are peptic ulcers treated?

To treat peptic ulcers, most people take medicines that reduce acid in the stomach. If you have an H. pylori infection, you'll also take antibiotics. You can help your ulcer heal by quitting smoking and avoiding alcohol. Using medicines such as aspirin, ibuprofen, or naproxen may increase the chance of your ulcer returning.

Information about Peptic Ulcer Disease

Current as of: October 19, 2024

Author: Ignite Healthwise, LLC Staff

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