Carnosine
Uses
Carnosine is a small molecule composed of the amino acids, histidine and alanine. It is found in relatively high concentrations in several body tissues—most notably in skeletal muscle, heart muscle, and brain.1, 2
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3 StarsReliable and relatively consistent scientific data showing a substantial health benefit.
2 StarsContradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1 StarFor an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
This supplement has been used in connection with the following health conditions:
| Used for | Why |
|---|---|
2 Stars Peptic Ulcer (Zinc) 150 mg of zinc carnosine complex twice per day | Studies have shown that a zinc salt of the amino acid carnosine protects against ulcer formation and promotes the healing of existing ulcers. Experimental animal studies have shown that a zinc salt of the amino acid exerts significant protection against ulcer formation and promotes the healing of existing ulcers. However, because zinc by itself has been shown to be helpful against peptic ulcer, it is not known how much of the beneficial effect was due to the carnosine. Clinical studies in humans demonstrated that this compound can help eradicate H. pylori, an organism that has been linked to peptic ulcer and stomach cancer. The amount of the zinc carnosine complex used in research studies for eradication of H. pylori is 150 mg twice daily. |
1 Star Peptic Ulcer Refer to label instructions | Carnisone may protect against ulcer formation and promote the healing of existing ulcers. Experimental animal studies have shown that a zinc salt of the amino acid exerts significant protection against ulcer formation and promotes the healing of existing ulcers. However, because zinc by itself has been shown to be helpful against peptic ulcer, it is not known how much of the beneficial effect was due to the carnosine. Clinical studies in humans demonstrated that this compound can help eradicate H. pylori, an organism that has been linked to peptic ulcer and stomach cancer. The amount of the zinc carnosine complex used in research studies for eradication of H. pylori is 150 mg twice daily. |
1 Star Wound Healing Refer to label instructions | Carnosine, a small molecule composed of the amino acids histidine and alanine, appears to promote wound healing. |
How It Works
How to Use It
For eradication of H. pylori, the amount of the zinc carnosine complex used in research studies was 150 mg twice daily. Due to the lack of human clinical trials, recommended levels for other applications are not known at this time.
Where to Find It
Dietary sources of preformed carnosine include meat and poultry and fish.
Possible Deficiencies
Carnosine deficiency may occur in severe protein deficiency and in certain severe genetic disorders characterized by inborn errors in amino acid metabolism.
Interactions
Interactions with Supplements, Foods, & Other Compounds
Interactions with Medicines
Side Effects
Side Effects
References
1. Quinn PJ, Boldyrev AA, Formazuyk VE. Carnosine: its properties, functions and potential therapeutic applications. Mol Aspects Med 1992;13:379-444.
2. Bonfanti L, Peretto P, De Marchis S, Fasolo A. Carnosine-related dipeptides in the mammalian brain. Prog Neurobiol 1999;59:333-53.
Last Review: 03-24-2015
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.
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