Nifedipine
Drug Information
Nifedipine is a calcium channel blocker used to treat angina pectoris and high blood pressure.
Common brand names:
Adalat CC, Procardia, Procardia XL, Nifediac CC, Nifedical XLSummary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
none
Reduce Side Effects
none
Support Medicine
none
Reduces Effectiveness
none
Potential Negative Interaction
none
Explanation Required
Ingestion of grapefruit juice has been shown to increase the absorption of felodipine (a drug similar in structure and action to that of nifedipine) and to increase the adverse effects of the medication in patients with hypertension. People taking nifedipine or similar drugs should not consume grapefruit juice or grapefruit, unless they have discussed it with their physician.
- Pleurisy Root
As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence. Pomegranate juice has been shown to inhibit the same enzyme that is inhibited by grapefruit juice. The degree of inhibition is about the same for each of these juices. Therefore, it would be reasonable to expect that pomegranate juice might interact with nifedipine in the same way that grapefruit juice does.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Last Review: 03-18-2015
![Aisle7 Logo](https://content.healthwise.net/resources/14.0/en-us/media/medical/cam/a7_a7logocpyrt105.gif)
Copyright © 2024 TraceGains, Inc. All rights reserved.
Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. The TraceGains knowledgebase does not contain every possible interaction.
Learn more about TraceGains, the company.
The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.
Topic Contents
This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.