Alprazolam
Drug Information
Alprazolam is used to treat anxiety and panic disorder, and is in a family of drugs known as benzodiazepines.
Common brand names:
Niravam, Xanax, Xanax XRSummary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
none
Reduce Side Effects
none
Support Medicine
- Vinpocetine
In a preliminary trial, an extract of periwinkle called vinpocetine was shown to produce minor improvements in short-term memory among people taking flunitrazepam, a benzodiazepine. Further study is needed to determine if vinpocetine would be a helpful adjunct to use of benzodiazepines, or alprazolam specifically.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Reduces Effectiveness
none
Potential Negative Interaction
- St. John’s WortSt. John's wort increases the activity of an enzyme in the body that metabolizes alprazolam. Consequently, supplementation with St. John's wort may increase the metabolism of, and therefore reduce the activity of, alprazolam.
- Kava
Kava (Piper methysticum) is an herb used to treat anxiety disorder. One individual who took alprazolam and kava together, along with two other medications (cimetidine and terazosin) was hospitalized in a lethargic and disoriented condition. Further research is needed to determine whether the combination of kava and alprazolam produces an adverse interaction. However, individuals should not take alprazolam and kava together unless supervised by a doctor.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Explanation Required
none
Last Review: 03-18-2015
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