Rizatriptan
Drug Information
Common brand names:
Maxalt, Maxalt-MLTSummary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
none
Reduce Side Effects
none
Support Medicine
Though food does not significantly interfere with the overall effectiveness of triptans, it may slow the onset of action of sumatriptan and rizatriptan. Therefore, these drugs are best taken on an empty stomach. However, taking eletriptan with a high-fat meal increases overall absorption of the drug.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Reduces Effectiveness
none
Potential Negative Interaction
- L-Tryptophan
Triptans work by stimulating serotonin receptors in the brain. 5-HTP (5-Hydroxytryptophan) and L-tryptophan are converted to serotonin in the brain, and taking them at the same time as 5-HT1 agonists could increase unwanted side effects. However, at the time of this writing there are no known interactions with 5-HT1 agonists and 5-HTP or L-tryptophan.
Explanation Required
- 5-HTP
Triptans work by stimulating serotonin receptors in the brain. 5-HTP (5-Hydroxytryptophan) and L-tryptophan are converted to serotonin in the brain, and taking them at the same time as 5-HT1 agonists could increase unwanted side effects. However, at the time of this writing there are no known interactions with 5-HT1 agonists and 5-HTP or L-tryptophan.
Last Review: 03-24-2015
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