Top of the page

Oral Electrolytes

Drug Information

Common brand names:

Enfamil Enfalyte, Pedialyte, Rehydralyte

Summary of Interactions with Vitamins, Herbs, & Foods

What Are Nutrient Interactions
Types of interactions:BeneficialAdverseCheck

Replenish Depleted Nutrients

  • Folic Acid

    Folic acid is needed by the body to utilize vitamin B12. Antacids, including sodium bicarbonate, inhibit folic acid absorption. People taking antacids are advised to supplement with folic acid.

  • Iron

    In a study of nine healthy people, sodium bicarbonate administered with 10 mg of iron led to lower iron levels compared to iron administered alone. This interaction may be avoided by taking sodium bicarbonate-containing products two hours before or after iron-containing supplements.

    The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Reduce Side Effects

  • none

Support Medicine

  • none

Reduces Effectiveness

  • none

Potential Negative Interaction

  • Calcium

    People with kidney failure may develop high blood levels of calcium while taking calcium acetate. Since calcium acetate is a source of supplemental calcium, people taking the drug should avoid taking additional calcium supplements. People experiencing adverse effects of high blood calcium—such as loss of appetite, mental depression, poor memory, and muscle weakness—should notify their healthcare practitioner.

Explanation Required

  • none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.