PE-PPA-Phenir-Pyril-Hydrocod
Drug Information
Summary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
none
Reduce Side Effects
none
Support Medicine
none
Reduces Effectiveness
none
Potential Negative Interaction
Ephedra is the plant from which the drug ephedrine was originally isolated. Phenylpropanolamine and ephedrine have similar effects and side effects. Until 2004, ephedra, also called ma huang, was used in many herbal products including supplements promoted for weight loss.
While interactions between phenylpropanolamine and ephedra have not been reported, it seems likely that such interactions could occur. To prevent potential problems, people taking phenylpropanolamine-containing products should avoid using ephedra/ephedrine-containing products.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Explanation Required
none
Last Review: 03-24-2015
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