Tezepelumab Prefilled Syringe (TEZEPELUMAB - INJECTION)

Instructions

This medicine is injected into the skin. Ask your doctor, nurse, or pharmacist where on your body this medicine can be injected and how to inject it.

Read and make sure you understand the instructions for measuring dose and using syringe. If you have any questions, talk to your doctor, nurse, or pharmacist.

The liquid should be clear or light yellow.

Check the medicine before each use. If the liquid medicine has any particles in it, appears discolored, or if the vial appears damaged, do not use it.

Do not shake the medicine before using.

Keep medicine in refrigerator. Do not freeze. Protect from light.

Keep the medicine in its original container.

You may store this medicine at room temperature for up to 30 days. Do not put back in refrigerator.

Take the medicine out of the refrigerator about 60 minutes before use to warm to room temperature.

Discard unused medicine after 30 days at room temperature.

Never use any medicine that has expired.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

Wash your hands before and after handling this medicine.

Clean the injection site with alcohol before applying the injector.

Do not inject into skin that is bruised, tender, red, hard or has scars or stretch marks.

Change location of injection each time.

Do not rub or massage the area where the injection was given.

If you miss a dose that is given by a health care provider, call them immediately for a new dosing schedule. If you are using this medicine at home and miss a dose, use it as soon as you remember. Use your next dose at the regular time. Do not use 2 doses at once.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Do not suddenly stop taking this medicine. Check with your doctor before stopping.

If you need to stop this medicine, your doctor may wish to gradually reduce the dosage before stopping.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

Speak with your health care provider before receiving any vaccinations.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• pain, redness, swelling near injection

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• worsening breathing symptoms

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.