Luspatercept Injection (LUSPATERCEPT - INJECTION)

This medicine is used for the following purposes:

  • anemia
  • blood cell disorder

Brand Name(s): Reblozyl

Generic Name: Luspatercept

Instructions

This medicine is given as an injection.

This medicine should be given by a trained health care provider.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

If possible, avoid using with alcohol, marijuana, or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.

Do not breastfeed while on this medicine. You may safely start breastfeeding 3 months after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Women of childbearing age should have a negative pregnancy test before starting this medicine.

Women must use reliable forms of birth control while taking this medicine and for 3 months after stopping to prevent pregnancy.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • diarrhea
  • dizziness
  • lack of energy and tiredness
  • headaches
  • high blood pressure
  • joint or muscle pain
  • nausea

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • severe back pain
  • loss of bladder control
  • chest or jaw pain
  • confusion
  • fainting
  • numbness or tingling in hands and feet
  • severe or persistent headache
  • sudden leg pain, swelling, warmth or redness
  • inability to move
  • shortness of breath
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • excessive or unusual sweating
  • sudden change or loss of vision

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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