For treating cancer.
Brand Name(s): Vitrakvi
Generic Name: Larotrectinib
Instructions
This medicine may be taken with or without food.
Swallow with a full glass (8 oz) of water unless your doctor gives you different instructions.
This medicine will work best if you take it at about the same time every day.
Keep the medicine in the refrigerator. Do not freeze.
Please ask your pharmacist how long you can use this medicine before you need to discard it.
Avoid grapefruit and grapefruit juice while on this medicine.
If you vomit after taking a dose, do not take an extra dose. Take your next dose at the usual time.
It is important that you keep taking each dose of this medicine on time even if you are feeling well.
If you forget to take a dose on time, take it as soon as you remember. If it is less than 6 hours to the next dose, do not take the missed dose. Return to your normal dosing schedule. Do not take 2 doses of this medicine at one time.
Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.
Tell your doctor if symptoms do not get better or if they get worse.
Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.
Keep all appointments for medical exams and tests while on this medicine.
Cautions
Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.
Do not use the medication any more than instructed.
If possible, avoid using with alcohol, marijuana, or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.
Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.
Do not breastfeed while on this medicine. You may safely start breastfeeding 1 week after stopping treatment.
This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.
Women must use reliable forms of birth control while taking this medicine and for 1 week after stopping to prevent pregnancy.
Men with a female partner who is of childbearing age must use reliable birth control during sexual activity while taking this medicine and for 1 week after stopping to prevent pregnancy.
Do not take St. John's wort while on this medicine.
Do not share this medicine with anyone who has not been prescribed this medicine.
Side Effects
The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.
- constipation
- coughing
- dizziness
- swelling of the legs, feet, and hands
- lack of energy and tiredness
- nausea and vomiting
Call your doctor or get medical help right away if you notice any of these more serious side effects:
- agitated feeling or trouble sleeping
- decreased appetite
- loss of balance
- bone pain
- changes in memory, mood, or thinking
- depression or feeling sad
- pain, redness, swelling or blistering on hands, feet or elbows
- signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
- unsteadiness while walking
A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.
Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.
IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it. Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions. Always follow their advice.
There is a more complete description of this medicine available in English. Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.
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More information about LAROTRECTINIB - ORAL
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Selected from data included with permission and copyright by First DataBank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
Conditions of Use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express Terms of Use.
