Instructions
Swallow the medicine without crushing or chewing it.
Take on empty stomach - 1 hour before or 2 hours after eating.
Swallow with a full glass (8 oz) of water unless your doctor gives you different instructions.
Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.
Drink plenty of water while on this medicine.
Avoid grapefruit and grapefruit juice while on this medicine.
If you vomit after taking a dose, do not take an extra dose. Take your next dose at the usual time.
If you forget to take a dose on time, take it as soon as you remember. If it is less than 6 hours to the next dose, do not take the missed dose. Return to your normal dosing schedule. Do not take 2 doses of this medicine at one time.
Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.
Tell your doctor if symptoms do not get better or if they get worse.
Keep all appointments for medical exams and tests while on this medicine.
Brand Name(s): Koselugo
Generic Name: Selumetinib
Cautions
Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.
Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.
Do not use the medication any more than instructed.
Do not breastfeed while on this medicine. You may safely start breastfeeding 1 week after stopping treatment.
This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.
Women must use reliable forms of birth control while taking this medicine and for 1 week after stopping to prevent pregnancy.
Men with a female partner who is of childbearing age must use reliable birth control during sexual activity while taking this medicine and for 1 week after stopping to prevent pregnancy.
Do not take St. John's wort while on this medicine.
Do not share this medicine with anyone who has not been prescribed this medicine.
Side Effects
The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.
- diarrhea
- dry skin
- lack of energy and tiredness
- nausea and vomiting
- stomach upset or abdominal pain
Call your doctor or get medical help right away if you notice any of these more serious side effects:
- bleeding or bruising
- persistent diarrhea
- dizziness
- dry mouth
- swelling of the legs, feet, and hands
- eye pain, redness, or itching
- rapid heartbeat
- lightheadedness
- muscle pain or weakness
- shortness of breath
- excessive thirst
- unusual or unexplained tiredness or weakness
- difficulty or discomfort urinating
- blurring or changes of vision
- seeing halos or colors around lights
- sudden or unexplained change in weight
A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.
Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.
IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it. Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions. Always follow their advice.
There is a more complete description of this medicine available in English. Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.
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More information about SELUMETINIB - ORAL
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Selected from data included with permission and copyright by First DataBank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
Conditions of Use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express Terms of Use.
