Hizentra Prefilled Syringe 20% (20 mL) (IMMUNE GLOBULIN - SUBCUTANEOUS INJECTION)

For immune disorder.

Instructions

This medicine is given as a continuous infusion into the skin.

Carefully follow the instructions for preparing this medicine before injection.

The liquid should be clear and colorless.

Check the medicine before each use. If the liquid medicine has any particles in it, appears discolored, or if the vial appears damaged, do not use it.

Do not shake the medicine before using.

Keep medicine at room temperature. Protect from light.

Keep the medicine in its original container.

If the medicine becomes frozen, you will need to throw it away.

Do not store above 77 degrees F (25 degrees C).

Discard any remaining medicine after your dose is given.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

Wash your hands before and after handling this medicine.

Ask your doctor, nurse or pharmacist to show you how to use this medicine correctly.

Do not inject into skin that is red, swollen or itchy.

If your dose is 2 syringes or injections, inject each in 2 different locations.

Change the location of the injection each time. Choose a location at least 1 inch from the last injection.

Do not rub or massage the area where the injection was given.

Drink plenty of water while on this medicine.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine is associated with an increased risk of serious heart problems, heart attack, and stroke. Please speak with your doctor about the risks and benefits of using this medicine. Contact your doctor immediately if you experience chest pain or difficulty breathing.

This medicine is associated with an increased risk for serious blood clots. Speak with your doctor about the benefits and risks from using this medicine.

Do not use the medication any more than instructed.

Contact your doctor if you develop any signs of a new infection such as fever, cough, sore throat, or chills.

Wash your hands often and avoid close contact with people with infections such as colds and flu.

Speak with your health care provider before receiving any vaccinations.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Ask your pharmacist how to properly throw away used needles or syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • coughing
  • diarrhea
  • fever or chills
  • headaches
  • pain, redness, swelling near injection
  • nausea and vomiting
  • sore throat

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • rapid breathing
  • chest or jaw pain
  • pain in the eye
  • fainting
  • severe or persistent headache
  • sudden leg pain, swelling, warmth or redness
  • neck pain or stiffness
  • pale or blue skin, lips or fingernails
  • rapid heartbeat
  • sensitivity to light
  • shortness of breath
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • sweating
  • unusual or unexplained tiredness or weakness
  • increased urinary frequency
  • difficulty or discomfort urinating
  • urinating less often
  • blood in urine
  • dark urine
  • sudden or unexplained weight gain
  • yellowing of eyes or skin

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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