Brexanolone Injection (BREXANOLONE - INJECTION)

For depression or anxiety.

Brand Name(s): Zulresso

Generic Name: Brexanolone

Instructions

This medicine is given as a continuous infusion into a vein.

This medicine is given gradually through the IV line.

This medicine should be given over 60 hours.

This medicine should be given by a trained health care provider.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not operate machinery or drive while on this medicine.

Please check with your doctor before drinking alcohol while on this medicine.

If possible, avoid using with marijuana or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • dizziness
  • dry mouth
  • feeling of heat or flushing

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • agitated feeling or trouble sleeping
  • decreased awareness or responsiveness
  • drowsiness or sedation
  • fainting
  • restlessness
  • extreme or persistent sleepiness
  • suicidal thoughts

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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