Lenvatinib Oral Capsule (LENVATINIB - ORAL)

For treating cancer.

Brand Name(s): Lenvima

Generic Name: Lenvatinib

Instructions

Swallow the medicine without crushing or chewing it.

If you have trouble swallowing this medicine, ask your doctor or pharmacist for specific directions for mixing it with water or apple juice.

This medicine may be taken with or without food.

This medicine will work best if you take it at about the same time every day.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

If you forget to take a dose on time, take it as soon as you remember. If it is less than 12 hours to the next dose, do not take the missed dose. Return to your normal dosing schedule. Do not take 2 doses of this medicine at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Talk to your doctor before taking other medicines, including aspirins and ibuprofen containing products. Speak to your doctor about which medicines are safe to use while you are on this medicine.

Visit your dentist regularly. Proper care of your teeth is very important while taking this medicine. Brush your teeth and floss regularly.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Avoid touching any powder from an open or broken capsule. If the powder touches the skin, nose, or eyes, rinse thoroughly with water.

Wear disposable gloves when handling this medicine.

Always wash your hands after handling this medicine.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

May cause mouth sores. Brush teeth gently. Avoid products containing alcohol. Rinse mouth with a mixture of water and baking soda or salt.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Do not breastfeed while on this medicine. You may safely start breastfeeding 1 week after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

To prevent pregnancy, women must use reliable forms of birth control while taking this medicine and for 30 days after stopping it.

Women who are pregnant or in their childbearing years should not touch or handle this medicine. This medicine can be absorbed through the woman's skin and harm the unborn baby.

Do not share this medicine with anyone who has not been prescribed this medicine.

Always refill this medicine before it runs out.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • agitated feeling or trouble sleeping
  • decreased appetite
  • constipation or diarrhea
  • dry mouth
  • nosebleeds
  • lack of energy and tiredness
  • hair loss
  • headaches
  • hoarseness or throat irritation
  • mouth sores or irritation
  • joint or muscle pain
  • nausea and vomiting
  • stomach upset or abdominal pain
  • changes in taste or unpleasant taste

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • increased risk of bruising and bleeding
  • worsening chest pain or crushing feeling
  • confusion
  • coughing up blood or vomit that looks like coffee grounds
  • dizziness
  • swelling of the legs, feet, and hands
  • fainting
  • severe or persistent headache
  • fast or irregular heart beats
  • high blood pressure
  • jaw pain
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • mood changes
  • seizures
  • shortness of breath
  • bloody or dark, tarry stools
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • urinating less often
  • difficulty or discomfort urinating
  • dark urine
  • blurring or changes of vision
  • sudden or unexplained weight gain
  • slow wound healing

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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