TRANSFORM Study

About Posttraumatic Stress Disorder

Posttraumatic stress disorder (PTSD) is a condition which some people develop following a traumatic or stressful event, such as a car accident or a sexual assault. People with PTSD may experience symptoms such as having repeated upsetting dreams, intrusive thoughts about the event, strong avoidance or things that remind them of the event, trouble remembering details about the event, or feeling extremely jumpy or on guard. People with PTSD may experience these types of symptoms long after the event has actually happened, and these symptoms may interfere with a person's day-to-day life. 

Do you think you may have PTSD? Take this online quiz.

A score of 3 or above may indicate that you have PTSD. If you think you may have PTSD, this study could be a good fit for you. Learn more about the study below .  

Please note that this online assessment is not a substitute for clinical diagnosis or advice. If you are having current thoughts of hurting yourself or that you would be better off dead, call the National Suicide Prevention Lifeline at 988.

About the Study

This program is funded by a grant from the National Institutes of Mental Health and is partnered with federally qualified health centers. Our study team is based in Ann Arbor, MI at the University of Michigan/Michigan Medicine.  

The TRANSFORM study's goal is to develop a stepped-care talk therapy model for patients with PTSD. Specifically, we are testing whether beginning with one type of therapy is better than beginning with another type of therapy, and whether moving to a different type of therapy after four weeks is more helpful than staying with the same therapy, depending on how well it is working.

Individuals May Be Eligible to Participate If They:

  • Are 18 years or older 
  • Currently have PTSD (Posttraumatic stress disorder) 
  • Fluent in English 
  • Are willing/able to download a PTSD mobile app 
  • Are stable on psychiatric medications 
  • Are a patient at one of our participating sites  

Schedule a Screening

Participation at a Glance

Study Therapies

Treatment plan is chosen through randomization.

Full PE 

Full Prolonged Exposure (Full PE) therapy is a type of cognitive-behavioral treatment that focuses on decreasing symptoms of PTSD in four ways: education about treatment and common reactions to trauma, breathing retraining, in vivo exposure, and imaginal exposure. PE addresses symptoms by decreasing avoidance, one of the underlying causes of PTSD.  
 
Participants in this treatment arm will meet with their therapist weekly for 60-minute sessions.  

PE-PC 

Prolonged Exposure for Primary Care (PE-PC) is a briefer form of Full PE, designed specifically for primary care settings.
 
Participants in this treatment arm will meet with their therapist weekly for 30- 45 minute sessions.   

CS-PTSD Coach 

Clinician-Supported PTSD Coach (CS-PTSD Coach) is a therapeutic intervention designed to facilitate the use of a PTSD treatment app. In sessions, therapists will guide individuals on how to use the app to learn more about PTSD and how to manage the problems associated with PTSD.   
 
Participants in this treatment arm will meet with their therapist weekly for 30-minute sessions.  

Intervention Arms

Possible Treatment Plans (Decided by Randomization [Flip of a Coin Process])

  • Arm A: PE-PC : Weekly 30-45 minute sessions for 4 weeks → Session 4: Symptom Assessment → PE-PC: Every other week for 8 weeks 
  • Arm B: PE-PC: Weekly 30-45 minute sessions for 4 weeks → Session 4: Symptom Assessment → PE-PC: Weekly 30-45 minute sessions for 8 weeks  
  • Arm C: PE-PC: Weekly 30-45 minute sessions for 4 weeks → Session 4: Symptom Assessment → Full PE: Weekly 60-minute sessions for 8 weeks 
  • Arm D: CS-PTSD Coach: Weekly 30-minute sessions for 4 weeks → Session 4: Symptom Assessment → Self-Managed PTSD Coach App  
  • Arm E: CS-PTSD Coach: Weekly 30-minute sessions for 4 weeks → Session 4: Symptom Assessment → CS-PTSD Coach: Every other week for 8 weeks 
  • Arm F: CS-PTSD Coach: Weekly 30-minute sessions for 4 weeks → Session 4: Symptom Assessment → Full PE: Weekly 60-minute sessions for 8 weeks

Meet Our Research Team

Hello! Thank you for your interest in our research program! We are a team of researchers dedicated to improving treatments for PTSD and increasing accessibility to these effective treatments.
 

Participating Sites 

Cherry Health: Currently recruiting 

Family Medical Center of Michigan: Currently recruiting 

Sterling Area Health Center: Currently recruiting 

Hamilton Community Health Network: Currently recruiting

Grace Health: Not yet open to recruitment 

Genesee Community Health Centers: Not yet open to recruitment

Upper Great Lakes Family Health: Not yet open to recruitment 

Western North Carolina Community Health Services: Currently recruiting

 
Family Care Health Centers: Currently recruiting
 
CommUnityCare Health Centers: Currently recruiting
 
Unity Care NW: Currently recruiting

Contact Us

Phone: 734-647-6466 OR 734-998-6439
Email: transform-study@med.umich.edu
To learn more, visit UMHealthResearch.org
To Schedule an Eligibility Screening, click here.

Frequently Asked Questions

How long do I have to complete treatment?
You will have about 3 months from the date of enrollment to complete your therapy sessions.

What if I miss a therapy session?
Please contact your clinic if you are unable to attend a scheduled therapy session.

What if I miss a study interview/assessment?
Please contact us if you are unable to attend a scheduled interview.

When does my participation end?
Therapy sessions will continue for 1-3 months, depending on how much your PTSD symptoms improve in the first month. Participation in the study ends at 9 months, after you complete your 9-month follow-up interview and survey.

Do I have to pay for treatment/therapy sessions?
Your insurance will be billed for treatment/therapy sessions. Your insurance company may require you to pay a co-payment.

Will I be compensated for my time?
You will receive $20 - $60 for each survey and interview you complete, for a total of up to $235. You will not be compensated for attending therapy sessions.

What if I no longer want to participate?
Participation is always voluntary. You may withdraw from the study at any time. If you decide to discontinue study participate, please give us a call and let us know.

Can I complete interviews and surveys if I did not complete treatment?
Yes, you can still complete our study interviews and surveys, even if you did not complete all therapy sessions. It is important for us to get feedback from individuals who did and did not complete treatment.

When/how will I receive my gift cards?
You will receive separate gift cards for each study activity (e.g. survey or interview). We will submit the gift card request as soon as you complete the study activity. Depending on whether you have chosen electronic or physical gift cards, it may take 1-2 weeks to receive the gift card.