bexagliflozin
What is the most important information I should know about bexagliflozin?
You should not use bexagliflozin if you have severe kidney disease or diabetic ketoacidosis.
Bexagliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.
You can easily become dehydrated while taking this medicine, which can lead to severely low blood pressure or a serious electrolyte imbalance.
Bexagliflozin can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.
What is bexagliflozin?
Bexagliflozin is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus (not for type 1 diabetes).
Bexagliflozin may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking bexagliflozin?
You should not use bexagliflozin if you are allergic to it, or if you have:
- severe kidney disease (or if you are on dialysis).
Bexagliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.
Tell your doctor if you have ever had:
- type I diabetes or diabetic ketoacidosis;
- low blood pressure;
- bladder infections or other urination problems;
- a diabetic foot ulcer or amputation;
- circulation problems or nerve problems in your legs or feet;
- problems with your pancreas, including surgery;
- liver or kidney disease;
- if you drink alcohol often;
- if you also take blood pressure medication, including a diuretic ("water pill");
- if you have a planned surgery; or
- if you are eating less, there is a change in your diet, or you are on a low salt diet.
Follow your doctor's instructions about using this medicine if you are pregnant. Controlling diabetes is very important during pregnancy, and your dose needs may be different during each trimester.
You should not use bexagliflozin during the second or third trimester of pregnancy.
Do not breastfeed.
How should I take bexagliflozin?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take bexagliflozin in the morning with or without food.
Swallow the tablet whole and do not crush, or chew.
Your treatment may also include diet, exercise, weight control, and special medical care.
Your blood sugar will need to be checked on a regular basis, and you may need other medical tests.
Blood sugar can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals.
Low blood sugar (hypoglycemia) can make you feel very hungry, dizzy, irritable, or shaky. To quickly treat hypoglycemia, eat or drink hard candy, crackers, raisins, fruit juice, or non-diet soda. Your doctor may prescribe glucagon injection in case of severe hypoglycemia.
Tell your doctor if you have frequent symptoms of high blood sugar (hyperglycemia) such as increased thirst or urination. Ask your doctor before changing your medication dosage.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using bexagliflozin.
Your blood pressure may get too low while you are taking bexagliflozin. Call your doctor if you are sick with vomiting or diarrhea.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking bexagliflozin?
Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
What are the possible side effects of bexagliflozin?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Seek medical attention right away if you have signs of a genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.
Stop using bexagliflozin and call your doctor at once if you have:
- nausea, vomiting, stomach pain; or
- tiredness or trouble breathing.
Call your doctor at once if you have:
- signs of a bladder infection --pain or burning when you urinate, increased urination, blood in your urine, fever, pain in your pelvis or back;
- low blood sugar --headache, weakness, drowsiness, confusion, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or
- fever, feeling tired or uneasy, redness, swelling, pain or tenderness in your genital or anal area.
Common side effects may include:
- increased or urgent need to urinate large amounts or at night;
- pain and burning when you urinate; or
- vaginal itching or discharge.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect bexagliflozin?
Tell your doctor about all your other medicines, especially:
- diabetes medications.
This list is not complete. Other drugs may affect bexagliflozin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Where can I get more information?
Your doctor or pharmacist can provide more information about bexagliflozin.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2023 Cerner Multum, Inc. Version: 1.02. Revision date: 2/13/2023.
This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.