mosunetuzumab
What is the most important information I should know about mosunetuzumab?
Tell your medical caregivers if you have symptoms of a serious side effect, such as fever, chills, trouble breathing, vomiting, or severe tiredness.
Call your doctor if you have signs and symptoms of neurological problems such as headache, dizziness, tremors, problems walking, confusion and disorientation, muscle problems or weakness.
Also call your doctor if you have signs of infection such as fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding
What is mosunetuzumab?
Mosunetuzumab is used to treat follicular lymphoma (a cancer of the lymphatic system) in adults whose cancer has returned or did not respond to another treatment and who have received at least two previous cancer treatments.
Mosunetuzumab may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before receiving mosunetuzumab?
Tell your doctor if you have or have ever had:
- an infusion reaction after receiving mosunetuzumab;
- an infection or an infection that lasts a long time or keeps returning; or
- Epstein-Barr Virus (mononucleosis).
You may need to have a negative pregnancy test before starting this treatment.
May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using mosunetuzumab and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using this medicine, and for at least 3 months after your last dose.
How is mosunetuzumab given?
Follow all directions on your prescription label and read all medication guides or instruction sheets.
Mosunetuzumab is given by a healthcare provider as an infusion into your vein. Your doctor will decide how many treatment cycles you will receive of this medicine.
You may be given other medications to help reduce your risk of cytokine release syndrome (CRS). Keep taking these medicines for as long as your doctor has prescribed.
Your healthcare provider will check for CRS while you are being treated with mosunetuzumab and may treat you in a hospital if you develop signs and symptoms of CRS.
Your treatment with mosunetuzumab may be temporarily or permanently discontinued if you have certain side effects.
You will need medical tests.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your mosunetuzumab injection.
What should I avoid while receiving mosunetuzumab?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
What are the possible side effects of mosunetuzumab?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.
Call your doctor at once if you have:
- signs and symptoms of nervous system disorders --headache; numbness or tingling in arms, legs, hands, or feet; dizziness, confusion, or disorientation; problems with balance, coordination, or muscle movement; sleepiness or sleeping problems; amnesia or forgetfulness; trouble speaking, writing, or reading; or seizures;
- low blood cell counts --fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;
- signs or symptoms of tumor related problems --chest pain, cough, breathing problems, tender or swollen lymph nodes, pain or swelling at tumor site; or
- signs of infection --fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding.
Common side effects may include:
- abnormal lab results;
- tiredness;
- rash;
- fever; or
- headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect mosunetuzumab?
Other drugs may affect mosunetuzumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Where can I get more information?
Your doctor or pharmacist can provide more information about mosunetuzumab.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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