eflapegrastim

What is the most important information I should know about eflapegrastim?

What is eflapegrastim?

Eflapegrastim is used in adults to treat neutropenia, a lack of certain white blood cells caused by cancer, chemotherapy, or by other conditions.

Eflapegrastim is used in adults to treat neutropenia, a lack of certain white blood cells caused by cancer, bone marrow transplant, receiving chemotherapy, or by other conditions.

Eflapegrastim may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving eflapegrastim?

Tell your doctor if you have ever had:

• sickle cell disorder; or
• kidney disease.

Tell your doctor if you are pregnant or breastfeeding.

How is eflapegrastim given?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Eflapegrastim is injected under the skin by a healthcare provider.

You will receive 1 injection of eflapegrastim for each cycle of chemotherapy. You should not receive this medicine for 14 days before or within 24 hours after your dose of chemotherapy.

You will need frequent medical tests.

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while receiving eflapegrastim?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

What are the possible side effects of eflapegrastim?

Capillary leak syndrome is a rare but serious side effect. Call your doctor right away if you have signs of this condition: stuffy or runny nose followed by tiredness, thirst, decreased urination, trouble breathing, and sudden swelling or weight gain.

Call your doctor at once if you have:

• shortness of breath or rapid breathing;
• pain or trouble breathing;
• easy bruising, unusual bleeding, purple or red spots under your skin;
• abdominal pain, tiredness, back pain;
• signs of infection -- fever, chills, sore throat, body aches, unusual tiredness, loss of appetite; or
• kidney problems --little or no urinating, blood in your urine, swelling in your face or ankles.

Common side effects may include:

• nausea, diarrhea;
• bone, muscle, or joint pain;
• back pain;
• headache;
• tiredness;
• rash;
• fever; or
• pale skin, feeling light-headed or short of breath, cold hands and feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect eflapegrastim?

Other drugs may affect eflapegrastim, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Your doctor or pharmacist can provide more information about eflapegrastim.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 1.01. Revision date: 12/19/2022.