lacosamide (oral/injection)

What is the most important information I should know about lacosamide?

Do not stop using lacosamide suddenly or you may have increased seizures.

Some people have thoughts about suicide while using lacosamide. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

What is lacosamide?

Lacosamide is used to treat partial onset seizures in adults and children who are at least 4 years old.

Lacosamide is also used to treat primary generalized tonic-clonic seizures in people who are at least 4 years old.

Lacosamide may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using lacosamide?

Tell your doctor if you have ever had:

• heart problems;
• kidney disease;
• liver disease;
• depression, a mood disorder, suicidal thoughts or actions;
• drug or alcohol addiction; or
• nerve problems caused by diabetes.

Lacosamide oral solution may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

Some people have thoughts about suicide while using lacosamide. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Do not start or stop using seizure medication during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of lacosamide on the baby.

How should I use lacosamide?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Lacosamide oral is taken by mouth. Lacosamide injection is given as an infusion into a vein. A healthcare provider will give you this injection if you are unable to take the medicine by mouth.

Lacosamide doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.

Lacosamide tablets or oral solution can be taken with or without food.

Measure oral solution carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Do not stop using lacosamide suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.

Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

What should I avoid while using lacosamide?

What are the possible side effects of lacosamide?

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

• a light-headed feeling, like you might pass out;
• severe dizziness;
• problems with balance or muscle movement;
• chest pain, shortness of breath;
• fast or pounding heartbeats;
• very slow heartbeats; or
• dark urine.

Common side effects may include:

• headache, dizziness;
• drowsiness;
• double vision; or
• nausea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1 800 FDA 1088.

What other drugs will affect lacosamide?

Tell your doctor about all your other medicines, especially:

• heart or blood pressure medication.

This list is not complete. Other drugs may affect lacosamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about lacosamide.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 12.01. Revision date: 12/29/2020.