solifenacin

What is the most important information I should know about solifenacin?

What is solifenacin?

Solifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

Solifenacin oral suspension (liquid), Vesicare LS is used to treat overactive bladder caused by a neurologic disorder (such as multiple sclerosis or spinal cord injury) in children at least 2 years old when other medicines cannot be used or have not worked.

Solifenacin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking solifenacin?

• untreated or uncontrolled narrow-angle glaucoma;
• a stomach disorder causing delayed emptying; or
• if you are unable to urinate.

Tell your doctor if you have ever had:

• glaucoma;
• liver disease;
• kidney disease;
• trouble emptying your bladder (or you have a weak stream of urine);
• slow digestion;
• a blockage in your stomach or intestines; or
• long QT syndrome.

How should I take solifenacin?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Solifenacin is usually taken once per day with or without food. Follow your doctor's instructions.

After taking solifenacin liquid drink a glass of water or milk. Avoid taking the liquid with food or other drinks or you may have a bitter aftertaste.

What happens if I miss a dose?

Tablets: Skip the missed dose and use your next dose at the regular time. Do not take 2 doses on the same day.

Oral suspension: Take the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose. Do not take two doses at one time.

What happens if I overdose?

What should I avoid while taking solifenacin?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Solifenacin can decrease perspiration and you may be more prone to heat stroke.

What are the possible side effects of solifenacin?

• severe stomach pain, or constipation for 3 days or longer;
• pain or burning when you urinate;
• headache, confusion, drowsiness, hallucinations;
• vision changes, eye pain, or seeing halos around lights;
• little or no urination, pain or burning when you urinate;
• dehydration symptoms --dizziness, tiredness, feeling very thirsty or hot, decreased sweating, or hot and dry skin; or
• high potassium level --nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects may include:

• blurred vision;
• dry mouth, dry eyes;
• painful urination;
• constipation; or
• heat stroke --decreased sweating, dry skin, dizziness, tiredness, nausea, feeling hot.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect solifenacin?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect solifenacin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about solifenacin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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