tiagabine

What is the most important information I should know about tiagabine?

Do not stop using tiagabine suddenly. Stopping suddenly may cause increased seizures.

What is tiagabine?

Tiagabine is an anti-epileptic medication, also called an anticonvulsant.

Tiagabine is used in combination with other medications to treat partial seizures in adults and children who are at least 12 years old.

Tiagabine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking tiagabine?

Tell your doctor about all other seizure medications you currently use. The safest dose of tiagabine may depend what other medicines you take in combination with it.

To make sure tiagabine is safe for you, tell your doctor if you have:

• a confirmed diagnosis of epilepsy;
• a history of a seizure that did not stop (also called status epilepticus);
• liver disease;
• a history of abnormal brain wave test (EEG); or
• a history of depression, mood disorder, or suicidal thoughts or actions.

Some people have thoughts about suicide while taking seizure medication. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of tiagabine on the baby.

How should I take tiagabine?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Tiagabine is often given in combination with other medications. Your dose of tiagabine may need to be changed if you start or stop using other seizure medicines.

Follow your doctor's dosing instructions very carefully.

Your doctor will need to check your progress while you are using tiagabine. To make sure you are taking a safe dose of tiagabine, your blood may need to be tested on a regular basis.

Use tiagabine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Do not stop using tiagabine suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Overdose symptoms may include slurred speech, severe weakness or drowsiness, muscle stiffness, problems with coordination, confusion, increased seizures, or feeling hostile or agitated.

What should I avoid while taking tiagabine?

What are the possible side effects of tiagabine?

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

• new or worsened seizures;
• confusion, extreme weakness;
• a light-headed feeling, like you might pass out;
• vision problems; or
• severe skin reaction --fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

• tiredness, lack of energy;
• dizziness, drowsiness;
• nausea, stomach pain;
• feeling nervous or irritable;
• tremors; or
• trouble concentrating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect tiagabine?

Tell your doctor about all your current medicines and any you start or stop using, especially:

• medicine to treat a psychiatric disorder;
• diet pills, stimulants, or ADHD medication;
• narcotic medicine; or
• other seizure medicines--carbamazepine, phenytoin, phenobarbital, primidone, valproate.

This list is not complete. Other drugs may interact with tiagabine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about tiagabine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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