brompheniramine, dextromethorphan, and pseudoephedrine

What is the most important information I should know about this medicine?

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

What is brompheniramine, dextromethorphan, and pseudoephedrine?

Brompheniramine is an antihistamine. Dextromethorphan is a cough suppressant. Pseudoephedrine is a decongestant.

Brompheniramine, dextromethorphan, and pseudoephedrine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, and watery eyes caused by allergies or the common cold.

Brompheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking this medicine?

• severe high blood pressure; or
• severe coronary artery disease (clogged arteries).

Do not use brompheniramine, dextromethorphan, and pseudoephedrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Tell your doctor if you have ever had:

• asthma or COPD (chronic obstructive pulmonary disease);
• a cough with mucus, or a cough caused by smoking, asthma, or emphysema;
• a blockage in your digestive tract (stomach or intestines);
• a bladder obstruction or other urination problems;
• high blood pressure, heart disease;
• glaucoma;
• diabetes; or
• overactive thyroid.

Tell your doctor if you are pregnant.

How should I take this medicine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Measure liquid medicine with the supplied measuring device (not a kitchen spoon).

If you need surgery or medical tests, tell the doctor ahead of time if you have taken this medicine within the past few days.

What happens if I miss a dose?

This medicine is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

What happens if I overdose?

Overdose symptoms may include feeling depressed or restless, fast or irregular heartbeats, severe drowsiness, loss of coordination, or seizure.

What should I avoid while taking this medicine?

Ask a doctor or pharmacist before taking other cough or cold medicines that may contain similar ingredients.

Avoid becoming overheated or dehydrated during exercise and in hot weather. This medicine can decrease sweating and you may be more prone to heat stroke.

What are the possible side effects of this medicine?

• hallucinations;
• a seizure;
• painful or difficult urination;
• a light-headed feeling, like you might pass out;
• fast or pounding heartbeats;
• pale skin, weakness, easy bruising or bleeding, fever, chills, body aches; or
• severe headache, blurred vision, pounding in your neck or ears.

Common side effects may include:

• dizziness, drowsiness;
• coughing up thick mucus;
• feeling restless or excited (especially in children); or
• dry mouth, nose, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect this medicine?

Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about brompheniramine, dextromethorphan, and pseudoephedrine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 8.01. Revision date: 10/6/2021.